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LUNG DISEASE

Chronic Obstructive Pulmonary Disease (COPD)

Chronic obstructive pulmonary disease (COPD) is one of the most common lung diseases. It makes it difficult to breathe. There are two main forms of COPD: chronic bronchitis, which involves a long-term cough with mucus, and emphysema, which involves destruction of the lungs over time. Most people with COPD have a combination of both conditions. Smoking is the leading cause of COPD. Standard treatment includes the use of bronchodilator inhalers, steroids, and supplemental oxygen.  Research…

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ASTHMA DEGENERATIVE DISEASE

Asthma is a common chronic inflammatory disease of the airways characterized by symptoms including wheezing, coughing, chest tightness, and shortness of breath, reversible airflow obstruction, and bronchospasm. Asthma is clinically classified according to the frequency of symptoms, forced expiratory volume in 1 second (FEV1), and peak expiratory flow rate.[3] Asthma may also be classified as atopic (extrinsic) or non-atopic (intrinsic). It can be exercised induced or occupational. Asthma affects an estimated 300 million people worldwide and caused 250,000 deaths in…

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CONGESTIVE HEART FAILURE AND CARDIOMYOPATHY

Congestive heart failure (CHF) is responsible for many one million hospitalizations in the U.S. and is considered the main cause or contributor to 53,000 deaths each year in the United States. CHF is associated with cardiomyopathy. Cardiomyopathy (deterioration in heart muscles) is commonly caused by coronary vessel disease but can also be due to infection and other causes. In this condition, the heart loses its ability to pump blood efficiently.  Cell therapy potentially offers an important solution for CHF and…

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POST MI MYOCARDIAL INFRACTION

Myocardial infarction (also known as heart attack) is responsible for significant cardiac destruction due to ischemia (lack of blood flow). This can lead to further or recurrent infarct and chronic angina. This problem is caused most commonly by coronary vessel disease which is very common in the United States and associated with significant morbidity.  Cell therapy potentially offers an important solution for chronic ischemia. During cardiac ischemia, millions of myocytes are lost resulting in loss of contractile function. One of…

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ASTHMA

Asthma is a common chronic inflammatory disease of the airways characterized by symptoms including wheezing, coughing, chest tightness, and shortness of breath, reversible airflow obstruction, and bronchospasm. Asthma is clinically classified according to the frequency of symptoms, forced expiratory volume in 1 second (FEV1), and peak expiratory flow rate. Asthma may also be classified as atopic (extrinsic) or non-atopic (intrinsic). It can be exercised induced or occupational. Asthma affects an estimated 300 million people worldwide and caused 250,000 deaths in…

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SHOULDER PROBLEMS

Shoulder problems come from chronic pain from rotator cuff injuries and arthritis of joints of the shoulder disables millions of Americans. Certain types of shoulder joint problems including certain tendon problems and ligamentous injuries may not be amenable to cell therapy. It is important to evaluate each individual case to assess likelihood of success with attempting regenerative therapy. We have developed a shoulder joint SVF deployment protocol that attempts to exploit the anti-inflammatory and healing effects of SVF (rich in…

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ELBOW AND HAND PROBLEMS

Elbow and Hand problems from arthritis of joints of the upper extremity is a form of degenerative joint disease that disables millions of Americans. Certain types of elbow and wrist joint problems including certain tendon problems and ligamentous injuries may not be amenable to cell therapy. It is important to evaluate each individual case to assess likelihood of success with attempting regenerative therapy. We have developed a degenerative joint disease SVF deployment protocol that attempts to exploit the anti-inflammatory and…

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HIP PROBLEMS

Hip arthritis is a form of degenerative joint disease that affects millions of Americans. Patients try to delay hip replacement surgery for as long as possible and often seek hip injections with steroids. Steroid injection is not favored as a viable long term treatment since the steroids actually damage local tissues over time. Certain types of hip problems including certain fractures and injuries may not be amenable to cell therapy. It is important to evaluate each individual case to assess…

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KNEE PROBLEMS

Knee arthritis is a form of degenerative joint disease that affects millions of Americans. There are several alternatives to knee surgery such as injection of cartilage substitutes or steroids. Steroid injection is not favored as a viable long term treatment since the steroids actually damage local tissues over time. Certain types of knee problems including significant meniscal and ligamentous injuries may not be amenable to regenerative therapy. It is important to evaluate each individual case to assess likelihood of success…

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BACK ARTHRITIS AND SPINE DISEASE

Back arthritis and Spine Disease have two common problems causing back pain, degenerative disk disease and facet arthropathy (a type of arthritis). Not all disk problems are amenable to regenerative therapy and patient selection is very important to optimize outcomes. Many forms of back pain are actually due to arthritis of the facet joints (small joints where vertebra connect to their adjacent neighboring vertebrae). We have developed a back arthritis and spine disease protocol that attempts to exploit the anti-inflammatory…

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NECK ARTHRITIS AND SPINE DISEASE

 Neck Arthritis and Spine disease have two common problems causing neck pain, degenerative disk disease and facet arthropathy (a type of arthritis) of the cervical spine. Not all disk problems are amenable to regenerative therapy and patient selection is very important to optimize outcomes. Many forms of spine pain are actually due to arthritis of the facet joints (small joints where vertebra connect to their adjacent neighboring vertebrae). We have developed a Neck Arthritis and Spine disease protocol that attempts…

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MALE INCONTINENCE

Post prostatectomy incontinence Protocol

In America alone, more than three million men are affected by loss of bladder control, a medical condition known as urinary incontinence. This problem has a great impact on health and quality of life for those who suffer with it. Male urinary incontinence is usually caused by a damaged sphincter, the circular muscle that controls the flow of urine out of the bladder. It often happens as the unavoidable result of prostate cancer surgery. When the…

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ERECTILE DYSFUNCTION

 Erectile Dysfunction (ED) is defined as the inability to achieve or sustain an erection suitable for sexual intercourse. ED affects up to one third of men of men throughout their lives and has a substantial negative impact on intimate relationships, quality of life and self-esteem. Causes are multifactorial but can be related to loss of testosterone, surgical damage to the penile nerves, medications, or other medical illnesses. The most common cause of ED is “vasculopathy”, which is damage to the…

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PEYRONIES DISEASE

Peyronies Disease “PD” has been described by experts as a physically and psychologically devastating problem manifested by a fibrous inelastic scar of the fibrous chambers of the penis known as the tunica albuginea. The scarring (known as “peyronies plaques”) can cause pain, bending, narrowing, hinging and shortening of the penis in the erect state. Recent demographic studies have shown that up to 9% of men have this problem and it seems to be even more prevalent after radical prostatectomy surgery.…

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INTERSTITIAL CYSTITIS

Millions of patients suffer from Interstitial Cystitis /painful bladder syndrome. This severe and debilitating condition has historically been confused with other bladder pathology which must be ruled out, making IC difficult to diagnose. Currently, Interstitial Cystitis/PBS is defined as “an unpleasant sensation (pain, pressure, discomfort) perceived to be related to the urinary bladder, associated with lower urinary tract symptoms of more than 6 weeks duration, in the absence of infection or other identifiable causes.” (2009 new American IC/BPS Guidelines). Although…

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STROKE

Stroke, also known as cerebro-vascular accident, is caused by a disturbance in blood supply to the brain. Stroke affects millions of Americans every year. The result is ischemic brain injury which means that part of the brain has suffered from lack of oxygen and this has resulted in vital tissue destruction. Symptoms vary depending on the anatomic location of the event and extent and duration of the tissue loss. After acute management, long term healing must occur which requires management…

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MUSCULAR DYSTROPHY

Muscular dystrophy (MD) is a disease characterized by progressive skeletal muscle weakness, defects in muscle proteins (dystrophin concentration is greatly reduced), and the death of muscle cells and tissue. Diagnosis is based on muscle biopsy, laboratory evaluation (increased levels of creatine phosphokinase) and EMG findings. There are nine major types of MD and most types of MD are multi-system disorders with manifestations in body systems including the heart, gastrointestinal system, nervous system, endocrine glands, eyes and brain. MD has a…

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PARKINSON’S

Parkinson’s Disease (PD) is a degenerative disorder of the central nervous system that affects close to one million Americans.  PD is a chronic and progressive disorder, which is thought to be caused by the destruction of dopamine (an important neurotransmitter) that generates cells in the midbrain.  The cause of PD is unknown and there is no cure.  Treatment is focused on medication and management of symptoms. Current research includes investigations into new animal models of the disease, and of the…

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ALS AMYOTROPHIC LATERAL SCLEROSIS

ALS also known as Lou Gehrig’s disease is a debilitating neurologic disease that results from the destruction of upper and lower motor neurons in the brain and spinal cord. ALS is associated with rapidly progressive weakness, muscle wasting, spasticity, and difficulty breathing, swallowing and speaking. There is no known cause for ALS and genetics are implicated in only 5% of cases. There is no known cure for the physical defects associated with ALS. Many investigators are looking at using the…

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PERIPHERAL NEUROPATHY

PN peripheral neuropathy is a degenerative disorder of the nerves (usually of the hands and feet) and has many causes including traumatic injuries, infections (neuritis), metabolic problems and exposure to toxins. One of the most common causes is diabetes, and many cases are due to auto-immune disorders, but frequently, the cause of neuropathy cannot be identified. PN Peripheral neuropathy often causes symptoms of numbness and pain described as burning or tingling. Physicians use a number of medications to reduce the…

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MULTIPLE SCLEROSIS

Multiple Sclerosis is a debilitating neurological disease that is thought to be caused by destruction of the myelin sheaths (fatty protective insulation) around axons of the brain and spinal cord. Loss of myelin impacts the ability of these tissues to conduct signals and the inflammatory process can lead to scarring resulting in a broad range of symptoms. This myelin damage appears to be related primarily to an auto-immune dysfunction, but there also appears to be environmental and genetic factors involved.…

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